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KMID : 0614619930250040713
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Korean Journal of Gastroenterology
1993 Volume.25 No. 4 p.713 ~ p.721
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Clinical Characteristics of Intrahepatic Choleithiasis in Korea
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김영호
김주성/김용태/윤용범/김정룡
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Abstract
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The incidence of intrahepatic cholelithiasis is higher in East Asia including Korea, than in the West There have been several clinical studies on intrahepatic cholelithiasis, but the subjects of those studies were limited to operated patients. In
this
study we analyzed 263 patients whose intrahepatic duct stones were confirmed not only by operation but also by radiologic studies. Among the patients, the male to female ratio was 1:1.5 and thitty-six percent of the patients had a past medical
history
of cholecystectomy. Involvement of both intrahepatic ducts was most common (39.5%) and stones were detected more frequently in the left intrahepatic duct (34.6%) than in the right (25.9%). Extrahepatic duct stones were found more frequently in
the
patients where both lobes were involved than in those with single lobe involvement. Regardless of the presence of acute cholangitis, one or more organisms grew in almost every bile culture (98%). In the detection of intrahepatic duct stones. the
sensitivity of computed tomography or percutaneous transhepatic cholangiography was higher than that of ultrasonography or endoscopic retrograde cholangiopancreatography. From the above results, we suggest that biliary bacterial infection may
play
an
important role in the pathophysiology of intrahepatic duct stones and that bile stasis also may play a considerable role. Further studies on efficient methods to diagnose and evaluate intrahepatic duct stones are needed in the future.
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KEYWORD
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